Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-Methyl-2-[2-(4-nitro-phenyl)-1-propyl-1H-indole-6-yloxy]-propanoic acid ethylester

HRID 66897Notes

Reaction equation

HRID 66897 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:11]([CH2:20][CH2:21][CH3:22])[C:12]3[C:17]([CH:18]=2)=[CH:16][CH:15]=[C:14]([OH:19])[CH:13]=3)=[CH:6][CH:5]=1)([O-:3])=[O:2].[CH2:23]([O:25][C:26](=[O:31])[C:27](Br)([CH3:29])[CH3:28])[CH3:24]>>[CH2:23]([O:25][C:26](=[O:31])[C:27]([CH3:29])([O:19][C:14]1[CH:13]=[C:12]2[C:17]([CH:18]=[C:10]([C:7]3[CH:8]=[CH:9][C:4]([N+:1]([O-:3])=[O:2])=[CH:5][CH:6]=3)[N:11]2[CH2:20][CH2:21][CH3:22])=[CH:16][CH:15]=1)[CH3:28])[CH3:24]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529102HCID 20529102, compound

Product 1

HCID 536627632-Methyl-2-[2-(4-nitro-phenyl)-1-propyl-1H-indole-6-yloxy]-propanoic acid ethylester

Procedure

The above compound was prepared from 2-(4-nitro-phenyl)-1-propyl-1H-indole-6-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-f204b56bc8b1445681fb325ea09d6550
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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