Propanoic acid, 2-bromo-2-methyl-, ethyl ester → 2-(3,4-Dibenzyl-1-propyl-1H-indole-5-yloxy)-2-methyl-propanoic acid ethylester

HRID 66903Notes

Reaction equation

HRID 66903 reaction equation
[CH2:1]([C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([OH:24])[C:15]=2[CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)[N:10]([CH2:25][CH2:26][CH3:27])[CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:28]([O:30][C:31](=[O:36])[C:32](Br)([CH3:34])[CH3:33])[CH3:29]>>[CH2:28]([O:30][C:31](=[O:36])[C:32]([O:24][C:14]1[C:15]([CH2:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:16]2[C:11](=[CH:12][CH:13]=1)[N:10]([CH2:25][CH2:26][CH3:27])[CH:9]=[C:8]2[CH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1)([CH3:34])[CH3:33])[CH3:29]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529223HCID 20529223, compound

Product 1

HCID 539270362-(3,4-Dibenzyl-1-propyl-1H-indole-5-yloxy)-2-methyl-propanoic acid ethylester

Procedure

The above compound was prepared from 3,4-dibenzyl-1-propyl-1H-indole-5-ol and 2-bromo-2-methyl-propanoic acid ethylester using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-0f0d9741e8524fa497011fd39022b6c1
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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