Propanoic acid, 2-bromo-2-methyl-, ethyl ester → HCID 20529113, compound

HRID 66904Notes

Reaction equation

HRID 66904 reaction equation
[C:1]1([C:7]2[N:8]([CH2:17][CH2:18][CH3:19])[C:9]3[C:14]([CH:15]=2)=[CH:13][C:12]([OH:16])=[CH:11][CH:10]=3)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.Br[C:21]([CH3:28])([CH3:27])[C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[CH2:25]([O:24][C:22](=[O:23])[C:21]([CH3:28])([O:16][C:12]1[CH:13]=[C:14]2[C:9](=[CH:10][CH:11]=1)[N:8]([CH2:17][CH2:18][CH3:19])[C:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)=[CH:15]2)[CH3:27])[CH3:26]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529085HCID 20529085, compound

Product 1

HCID 20529113HCID 20529113, compound

Procedure

The above compound was prepared from 2-phenyl-1-propyl-1H-indole-5-ol and ethyl 2-bromo-2-methyl-propanoate using a procedure analogous to that of Example 10.

Sources & evidence

ORD record
ord-c7bd02b82aec43f489de7adb60fd5fe0
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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