Propanoic acid, 2-bromo-2-methyl-, ethyl ester → Propanoic acid, 2-((2-(4-(acetylamino)phenyl)-1-propyl-1H-indol-5-yl)oxy)-2-methyl-, ethyl ester

HRID 66905Notes

Reaction equation

HRID 66905 reaction equation
[NH:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:12]([CH2:21][CH2:22][CH3:23])[C:13]3[C:18]([CH:19]=2)=[CH:17][C:16]([OH:20])=[CH:15][CH:14]=3)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3].Br[C:25]([CH3:32])([CH3:31])[C:26]([O:28][CH2:29][CH3:30])=[O:27]>>[NH:1]([C:5]1[CH:10]=[CH:9][C:8]([C:11]2[N:12]([CH2:21][CH2:22][CH3:23])[C:13]3[C:18]([CH:19]=2)=[CH:17][C:16]([O:20][C:25]([CH3:32])([CH3:31])[C:26]([O:28][CH2:29][CH3:30])=[O:27])=[CH:15][CH:14]=3)=[CH:7][CH:6]=1)[C:2]([CH3:4])=[O:3]

Participants

3

Reactant 2

HCID 11745Propanoic acid, 2-bromo-2-methyl-, ethyl esterHCID 20529159HCID 20529159, compound

Product 1

HCID 3059435Propanoic acid, 2-((2-(4-(acetylamino)phenyl)-1-propyl-1H-indol-5-yl)oxy)-2-methyl-, ethyl ester

Procedure

The above compound was prepared from 2-(4-acetamino-phenyl)-1-propyl-1H-indole-5-ol and ethyl 2-bromo-2-methyl-propanoate using a procedure analoguous to that of Example 10.

Sources & evidence

ORD record
ord-b97d12d736c04bafb0e1e3894df45a91
Source dataset
uspto-grants-1982_08
Patent number
US04343811

Reaction notes

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