Sodium ion → 2-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-pyridin-3-ol

HRID 669059Notes

Reaction equation

HRID 669059 reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH2:34]1[O:35][CH2:36][CH2:37][O:38][CH2:39]1.[CH3:1][C:2]1([CH3:3])[C:4]([CH3:5])([CH3:6])[O:7][B:8]([C:9]2=[CH:10][CH2:11][C:12]3([O:13][CH2:14][CH2:15][O:16]3)[CH2:17][CH2:18]2)[O:19]1.[I:20][c:21]1[n:22][cH:23][cH:24][cH:25][c:26]1[OH:27].[Na+:32].[Na+:33].[c:40]1([PH:41]([Pd-4:42]([PH:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)([c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[c:56]2[cH:57][cH:58][cH:59][cH:60][cH:61]2)([PH:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)([c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[c:75]2[cH:76][cH:77][cH:78][cH:79][cH:80]2)[PH:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)([c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[c:94]2[cH:95][cH:96][cH:97][cH:98][cH:99]2)([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)[c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[cH:112][cH:113][cH:114][cH:115][cH:116]1>>[C:9]1([c:21]2[n:22][cH:23][cH:24][cH:25][c:26]2[OH:27])=[CH:10][CH2:11][C:12]2([O:13][CH2:14][CH2:15][O:16]2)[CH2:17][CH2:18]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 971792-Iodopyridin-3-olHCID 36970768-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1,4-dioxaspiro(4.5)dec-7-eneHCID 178420553HCID 178420553, compound

Product 1

HCID 585625152-(1,4-Dioxa-spiro[4.5]dec-7-en-8-yl)-pyridin-3-ol

Sources & evidence

ORD record
ord-b4ef8a19ef384822afc218c4747af6f8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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