2-(Pyrrolidin-3-yl)pyridine → 1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(2-pyridinyl)-1-pyrrolidinyl]-1,8-naphthyridine-3-carboxylic acid

HRID 669093Notes

Reaction equation

HRID 669093 reaction equation
[Cl:1][c:2]1[c:3]([F:19])[cH:4][c:5]2[c:6](=[O:18])[c:7]([C:15](=[O:16])[OH:17])[cH:8][n:9]([CH:12]3[CH2:13][CH2:14]3)[c:10]2[n:11]1.[NH:20]1[CH2:21][CH:22]([c:25]2[n:26][cH:27][cH:28][cH:29][cH:30]2)[CH2:23][CH2:24]1>>[c:2]1([N:20]2[CH2:21][CH:22]([c:25]3[n:26][cH:27][cH:28][cH:29][cH:30]3)[CH2:23][CH2:24]2)[c:3]([F:19])[cH:4][c:5]2[c:6](=[O:18])[c:7]([C:15](=[O:16])[OH:17])[cH:8][n:9]([CH:12]3[CH2:13][CH2:14]3)[c:10]2[n:11]1

Participants

3

Reactant 2

HCID 50139382-(Pyrrolidin-3-yl)pyridineHCID 110551427-Chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid

Product 1

HCID 152303251-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-[3-(2-pyridinyl)-1-pyrrolidinyl]-1,8-naphthyridine-3-carboxylic acid

Sources & evidence

ORD record
ord-e7d93290e3e946f288e0df7ee2021f1e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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