HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → 2-[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methyl-propanoic acid amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Propanoic acid, 2-((3-(4-chlorophenyl)-1,2-dimethyl-1H-indol-5-yl)oxy)-2-methyl- | HCID 3059432 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 2-[3-(4-Chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methyl-propanoic acid amide | HCID 54257208 | — |
Reaction Steps
The above compound was prepared from 2-[3-(4-chlorophenyl)-1,2-dimethyl-1H-indole-5-yloxy]-2-methylpropanoic acid and a saturated solution of ammonia in absolute tetrahydrofurane using a procedure analogous to that of Example 130.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04343811 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-e9480fdab2254b11b87d25124bf29a3d |
| Source note | uspto-grants-1982_08 |