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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 66916Generated: October 29, 2026

Methylamine → 2-Methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]-propanoic acid methylamide

https://huagongshe.com/reaction/66916

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethylamineHCID 6329—
ReactantPropanoic acid, 2-methyl-2-((2-methyl-1-propyl-3-(4-pyridinyl)-1H-indol-5-yl)oxy)-, hydrochlorideHCID 3059433—
Solvent1,4-DioxaneHCID 31275—
Product2-Methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]-propanoic acid methylamideHCID 54030272—

Reaction Steps

The above compound was prepared from 2-methyl-2-[2-methyl-1-propyl-3-(4-pyridyl)-1H-indole-5-yloxy]propanoic acid hydrochloride and methylamine in dioxane using a procedure analogous to that of Example 128.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04343811
Source datasetuspto-grants-1982_08
ORD IDord-ec65866c75be4f978567e4f78a8a1742
Source noteuspto-grants-1982_08