N-Methylpiperazine-2-carboxamide → 4-[5-[[1-[[4-chloro-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-4-oxo-1,3-thiazol-2-yl]-N-methylpiperazine-2-carboxamide

HRID 669269Notes

Reaction equation

HRID 669269 reaction equation
[CH3:32][NH:33][C:34](=[O:35])[CH:36]1[NH:37][CH2:38][CH2:39][NH:40][CH2:41]1.[Cl:1][c:2]1[cH:3][c:4]([C:28]([F:29])([F:30])[F:31])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([S:22][CH2:23][CH3:24])[S:21]4)[cH:13][cH:14][c:15]23)[cH:26][cH:27]1>>[Cl:1][c:2]1[cH:3][c:4]([C:28]([F:29])([F:30])[F:31])[c:5]([CH2:6][n:7]2[n:8][cH:9][c:10]3[cH:11][c:12]([CH:16]=[C:17]4[C:18](=[O:25])[N:19]=[C:20]([N:40]5[CH2:39][CH2:38][NH:37][CH:36]([C:34]([NH:33][CH3:32])=[O:35])[CH2:41]5)[S:21]4)[cH:13][cH:14][c:15]23)[cH:26][cH:27]1

Participants

3

Reactant 2

HCID 14722545N-Methylpiperazine-2-carboxamideHCID 672401235-[1-(4-chloro-2-trifluoromethyl-benzyl)-1H-indazol-5-ylmethylene]-2-ethylsulfanyl-thiazol-4-one

Product 1

HCID 767563514-[5-[[1-[[4-chloro-2-(trifluoromethyl)phenyl]methyl]indazol-5-yl]methylidene]-4-oxo-1,3-thiazol-2-yl]-N-methylpiperazine-2-carboxamide

Sources & evidence

ORD record
ord-fd9f1f005c3345399183d3ace83d5f1b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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