Ethanol → 1-isopentyl-N-[4-[N-methyl-N-(tetrahydropyran-4-yl)aminomethyl]phenyl]-7-[4-(2-propoxyethoxy)phenyl]-2,3-dihydro-1-benzazepine-4-carboxamide
Reaction equation
[B:36]([O-:37])([O-:51])[O:52][c:38]1[cH:39][cH:40][c:41]([O:44][CH2:45][CH2:46][O:47][CH2:48][CH2:49][CH3:50])[cH:42][cH:43]1.[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:35]1)[CH:7]=[C:8]([C:17](=[O:18])[NH:19][c:20]1[cH:21][cH:22][c:23]([CH2:26][N:27]([CH:28]3[CH2:29][CH2:30][O:31][CH2:32][CH2:33]3)[CH3:34])[cH:24][cH:25]1)[CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][CH:14]([CH3:15])[CH3:16].[C:53](=[O:54])([O-:55])[O-:56].[CH2:61]([OH:62])[CH3:63].[K+:57].[K+:58].[OH2:59].[OH2:60].[c:64]1([CH3:65])[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[c:2]1(-[c:38]2[cH:39][cH:40][c:41]([O:44][CH2:45][CH2:46][O:47][CH2:48][CH2:49][CH3:50])[cH:42][cH:43]2)[cH:3][cH:4][c:5]2[c:6]([cH:35]1)[CH:7]=[C:8]([C:17](=[O:18])[NH:19][c:20]1[cH:21][cH:22][c:23]([CH2:26][N:27]([CH:28]3[CH2:29][CH2:30][O:31][CH2:32][CH2:33]3)[CH3:34])[cH:24][cH:25]1)[CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][CH:14]([CH3:15])[CH3:16]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-e83767b5423d4ddfa8615f273095415e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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