1-Isopropyl-7-nitro-1,3,4,5-tetrahydro-benzo[b]azepin-2-one → 3-[5-Chloro-2-(1-isopropyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-ylamino)-pyrimidin-4-ylamino]-bicyclo[2.2.1]hept-5-ene-2-carboxylic acid amide
Reaction equation
[CH:1]([CH3:2])([CH3:3])[N:4]1[c:5]2[c:6]([cH:12][c:13]([N+:16]([O-:17])=[O:18])[cH:14][cH:15]2)[CH2:7][CH2:8][CH2:9][C:10]1=[O:11].[Cl:19][c:20]1[n:21][cH:22][c:23]([Cl:37])[c:24]([NH:26][CH:27]2[CH:28]([C:34](=[O:35])[NH2:36])[CH:29]3[CH:30]=[CH:31][CH:32]2[CH2:33]3)[n:25]1>>[CH:1]([CH3:2])([CH3:3])[N:4]1[c:5]2[c:6]([cH:12][c:13]([NH:16][c:20]3[n:21][cH:22][c:23]([Cl:37])[c:24]([NH:26][CH:27]4[CH:28]([C:34](=[O:35])[NH2:36])[CH:29]5[CH:30]=[CH:31][CH:32]4[CH2:33]5)[n:25]3)[cH:14][cH:15]2)[CH2:7][CH2:8][CH2:9][C:10]1=[O:11]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-f4e27345a807459f96fdc22cfd23ad76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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