HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chlorobenzoyl chloride → HCID 13041521, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chlorobenzoyl chloride | HCID 69110 | — |
| Reactant | 3-(Trichloromethyl)-1,2,4-thiadiazol-5-amine | HCID 602848 | — |
| Solvent | O-Xylene | HCID 7237 | — |
| Product | HCID 13041521 | HCID 13041521 | 85% |
Reaction Steps
A solution of 10.9 g (0.05 mole) 5-amino-3-trichloromethyl-1,2,4-thiadiazole and 17.5 g (0.10 mole) 2-chlorobenzoyl chloride was heated at reflux for 18 hours in 200 ml xylene. After concentration in vacuo, the resulting oil was triturated with cold hexane to give 14.9 g (85% yield) of crude product. Recrystallization from benzene/hexane gave a pure product; m.p. 142° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04343945 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-f818592d5a6f467c9ae3c8dcdd18f1d6 |
| Source note | uspto-grants-1982_08 |