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HRID66944

反应详情

EQUATION

反应方程式

HRID 66944 的结构方程式

REACTANTS

反应物

2
结构：O=C(Cl)c1c(Cl)cccc1Cl
HCID78392

2,6-Dichlorobenzoyl chloride

C7H3Cl3O

结构：Nc1nc(C(Cl)(Cl)Cl)ns1
HCID602848

3-(Trichloromethyl)-1,2,4-thiadiazol-5-amine

C3H2Cl3N3S

PRODUCTS

生成物

1
结构：O=C(Nc1nc(C(Cl)(Cl)Cl)ns1)c1c(Cl)cccc1Cl
HCID13041523

未命名化合物

收率 22%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：Clc1ccc(Cl)cc1
溶剂HCID4685

1,4-Dichlorobenzene

C6H4Cl2

PROCEDURE

实验过程

A solution of 22.0 g (0.1 mole) 5-amino-3-trichloromethyl-1,2,4-thiadiazole and 20.1 g (0.1 mole) 2,6-dichlorobenzoyl chloride was refluxed for 8 hours in 200 ml dichlorobenzene. After filtration, the crude product precipitated from the filtrate upon standing. Recrystallization from toluene gave 8.6 g (22% yield) of pure product; m.p. 209° C.

WORKUP

后处理

  1. filtrationAfter filtration
  2. customthe crude product precipitated from the filtrate
  3. customRecrystallization from toluene