化工社化工社 化学情報印刷レポート · 研究参考用
1-Nitropropane → 1-Hydroxy-2-Ethylbenzimidazole-3-Oxide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-Nitropropane | HCID 7903 | — |
| 反応物 | Diethylamine | HCID 8021 | — |
| 反応物 | Benzofuroxan | HCID 68075 | — |
| 溶媒 | Tetrahydrofuran | HCID 8028 | — |
| 生成物 | 1-Hydroxy-2-Ethylbenzimidazole-3-Oxide | HCID 14549029 | — |
反応手順
To a mixture containing 1-nitropropane (10.7 g., 0.12 moles), benzofuroxan (13.6 g., 0.10 moles) and tetrahydrofuran (50 ml.) is added dropwise diethylamine (8.7 g., 0.12 moles). The reaction temperature rises almost to reflux on addition of amine. Upon completion, the mixture is allowed to cool and then sit overnight.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04343942 |
| 出典データセット | uspto-grants-1982_08 |
| ORD ID | ord-5eee42ca1ae243628b6315c46337862b |
| 出典メモ | uspto-grants-1982_08 |