Ethanolamine → N-Cyclopropyl-3-[3-[[1-[2-[2-[(2-hydroxyethyl)amino]ethoxy]phenyl]cyclobutyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzamide

HRID 669580Notes

Reaction equation

HRID 669580 reaction equation
[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([C:11]2([NH:15][c:16]3[c:17](=[O:35])[n:18](-[c:22]4[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]5[CH2:29][CH2:30]5)[cH:31][cH:32][c:33]4[CH3:34])[cH:19][cH:20][n:21]3)[CH2:12][CH2:13][CH2:14]2)[cH:7][cH:8][cH:9][cH:10]1.[NH2:36][CH2:37][CH2:38][OH:39]>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([C:11]2([NH:15][c:16]3[c:17](=[O:35])[n:18](-[c:22]4[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]5[CH2:29][CH2:30]5)[cH:31][cH:32][c:33]4[CH3:34])[cH:19][cH:20][n:21]3)[CH2:12][CH2:13][CH2:14]2)[cH:7][cH:8][cH:9][cH:10]1)[NH:36][CH2:37][CH2:38][OH:39]

Participants

3

Reactant 2

HCID 700EthanolamineHCID 666888223-(3-(1-(2-(2-Chloroethoxy)phenyl)cyclobutylamino)-2-oxopyrazin-1(2H)-yl)-N-cyclopropyl-4-methylbenzamide

Product 1

HCID 66688672N-Cyclopropyl-3-[3-[[1-[2-[2-[(2-hydroxyethyl)amino]ethoxy]phenyl]cyclobutyl]amino]-2-oxo-1(2H)-pyrazinyl]-4-methyl-benzamide

Sources & evidence

ORD record
ord-8d4e97a5654e49408c2d5ab498bc5f1f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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