4-Hydroxypyrrolidine → 1-{3-[4-(6-Bromo-3H-imidazo[4,5-b]pyridin-2-yl)phenoxy]-2-hydroxypropyl}pyrrolidin-3-ol
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9](-[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][CH:19]3[O:20][CH2:21]3)[cH:15][cH:16]1)[n:10]2.[NH:22]1[CH2:23][CH:24]([OH:27])[CH2:25][CH2:26]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][c:9](-[c:11]1[cH:12][cH:13][c:14]([O:17][CH2:18][CH:19]([OH:20])[CH2:21][N:22]3[CH2:23][CH:24]([OH:27])[CH2:25][CH2:26]3)[cH:15][cH:16]1)[n:10]2Participants
3
Sources & evidence
- ORD record
- ord-a2688e7d2a764272841c275bc17ac3a7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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