Bromide ion → 1-Benzyl-4-(2-fluorobenzyl)piperidin-4-ol
Reaction equation
[Br-:15].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH3:25][CH2:26][O:27][CH2:28][CH3:29].[F:16][c:17]1[c:18]([CH2:19][Mg+:20])[cH:21][cH:22][cH:23][cH:24]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][C:11]([OH:14])([CH2:19][c:18]2[c:17]([F:16])[cH:24][cH:23][cH:22][cH:21]2)[CH2:12][CH2:13]1Participants
5
Sources & evidence
- ORD record
- ord-d581105c920a4cf09ce2d2d40c87b393
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…