Phenylacetyl chloride → (4-nitrophenyl)methyl N-[1-[[2-phenyl-4-[(2-phenylacetyl)amino]cyclopentyl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate

HRID 670235Notes

Reaction equation

HRID 670235 reaction equation
[C:1]([CH3:3])([CH3:4])([O:5][C:6](=[O:2])[NH:8][CH:9]1[CH2:10][CH:11]([CH2:20][N:21]2[CH2:22][CH2:23][CH:24]([N:27]([CH2:28][CH:29]=[CH2:30])[C:31](=[O:32])[O:33][CH2:34][c:35]3[cH:36][cH:37][c:38]([N+:41](=[O:42])[O-:43])[cH:39][cH:40]3)[CH2:25][CH2:26]2)[CH:12]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:13]1)[CH3:7].[c:44]1([CH2:50][C:51]([Cl:52])=[O:53])[cH:45][cH:46][cH:47][cH:48][cH:49]1>>[O:5]=[C:6]([NH:8][CH:9]1[CH2:10][CH:11]([CH2:20][N:21]2[CH2:22][CH2:23][CH:24]([N:27]([CH2:28][CH:29]=[CH2:30])[C:31](=[O:32])[O:33][CH2:34][c:35]3[cH:36][cH:37][c:38]([N+:41](=[O:42])[O-:43])[cH:39][cH:40]3)[CH2:25][CH2:26]2)[CH:12]([c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[CH2:13]1)[CH2:50][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1

Participants

3

Reactant 2

HCID 7679Phenylacetyl chlorideHCID 181876031-(SR)-((t-Butoxycarbonyl)amino)-3-(SR)-((4-(N-(4-nitrobenzyloxycarbonyl)-N-(allyl)amino)piperidin-1-yl)methyl)-4-(SR)-phenylcyclopentane

Product 1

HCID 18372784(4-nitrophenyl)methyl N-[1-[[2-phenyl-4-[(2-phenylacetyl)amino]cyclopentyl]methyl]piperidin-4-yl]-N-prop-2-enylcarbamate

Sources & evidence

ORD record
ord-fa3a359299a0436a8e4d0cf982c48444
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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