Toluene → 6-chlorocarbonyl-3,4-dihydro-1H-isoquinoline-2-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:18](=[O:19])[OH:20])[cH:14][c:15]2[CH2:16][CH2:17]1.[CH3:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1.[S:21]([Cl:22])([Cl:23])=[O:24]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][c:10]2[cH:11][cH:12][c:13]([C:18](=[O:20])[Cl:23])[cH:14][c:15]2[CH2:16][CH2:17]1Participants
4
Sources & evidence
- ORD record
- ord-9d320cc1f3ae46a59390658fc667ded6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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