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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 670281Generated: October 29, 2026

Dimethyl Sulfoxide → 5-fluoro-2',2'-dimethylspiro[1H-indole-3,1'-cyclopropane]-2-one

https://huagongshe.com/reaction/670281

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethyl SulfoxideHCID 679—
ReactantSodium ionHCID 923—
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantIodide IonHCID 30165—
ReactantTrimethylsulfoxoniumHCID 74499—
ReactantHydrideHCID 166653—
Reactant5-Fluoro-3-isopropylidene-1,3-dihydro-indol-2-oneHCID 67230550—
Product5-fluoro-2',2'-dimethylspiro[1H-indole-3,1'-cyclopropane]-2-oneHCID 77251768—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-af6eb06294d04e6bbc585a67dc3d1e3c
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)