1-(Bromomethyl)-4-(trifluoromethyl)benzene → 6-Benzyl-2-(3,5-dichlorophenyl)-4-{[4-(trifluoromethyl)benzyl]oxy}-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

HRID 670313Notes

Reaction equation

HRID 670313 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[c:11]([n:12][c:13](-[c:17]3[cH:18][c:19]([Cl:24])[cH:20][c:21]([Cl:23])[cH:22]3)[n:14][c:15]2[OH:16])[CH2:25][CH2:26]1.[F:27][C:28]([c:29]1[cH:30][cH:31][c:32]([CH2:33][Br:34])[cH:35][cH:36]1)([F:37])[F:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][c:10]2[c:11]([n:12][c:13](-[c:17]3[cH:18][c:19]([Cl:24])[cH:20][c:21]([Cl:23])[cH:22]3)[n:14][c:15]2[O:16][CH2:33][c:32]2[cH:31][cH:30][c:29]([C:28]([F:27])([F:37])[F:38])[cH:36][cH:35]2)[CH2:25][CH2:26]1

Participants

3

Reactant 2

HCID 1230621-(Bromomethyl)-4-(trifluoromethyl)benzeneHCID 178517513HCID 178517513, compound

Product 1

HCID 691981346-Benzyl-2-(3,5-dichlorophenyl)-4-{[4-(trifluoromethyl)benzyl]oxy}-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine

Sources & evidence

ORD record
ord-ed031fe6abe549eab1bc5ee15de87c19
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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