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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 670332Generated: October 29, 2026

1,2-Dichloroethane → 4-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-ylmethyl]-piperidine-1-carboxylic acid amide

https://huagongshe.com/reaction/670332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2-DichloroethaneHCID 11—
ReactantTetrahydrofuranHCID 8028—
ReactantTrimethylsilyl isocyanateHCID 70696—
Reactant4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-1-piperidin-4-ylmethyl-piperazin-2-oneHCID 67014811—
Product4-[4-(6-Chloro-benzo[b]thiophene-2-sulfonyl)-2-oxo-piperazin-1-ylmethyl]-piperidine-1-carboxylic acid amideHCID 67015002—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-fdcf33e7665245c59ae5dc227aadfa61
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)