1-Benzyl-3-methyl-4-piperidone → 1-Benzyl-3-methyl-4-hydroxy-4-(benzofur-4-yl)piperidine
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]2[c:7]1[cH:8][cH:9][o:10]2.[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]1[CH2:19][CH:20]([CH3:25])[C:21](=[O:24])[CH2:22][CH2:23]1>>[c:2]1([C:21]2([OH:24])[CH:20]([CH3:25])[CH2:19][N:18]([CH2:11][c:12]3[cH:13][cH:14][cH:15][cH:16][cH:17]3)[CH2:23][CH2:22]2)[cH:3][cH:4][cH:5][c:6]2[c:7]1[cH:8][cH:9][o:10]2Participants
3
Sources & evidence
- ORD record
- ord-835f45d29e7d4cceb2b3c1df6dd212b2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…