Hydrochloric Acid → 3-Isopropylphenyl (chlorosulfinyl)(methyl)carbamate

Participants

Reaction Steps

Four grams 3-isopropylphenyl methylcarbamate were mixed with excess thionyl chloride and heated up to 80° C. until HCl evolution ceased. Excess thionyl chloride was removed by distillation and the residue was subjected to high vacuum (0.1 mm) for 1 hour. NMR of the residue in chloroform-d-TMS gave the following absorptions: δ7.5-6.9 (m, 4H, aromatic protons). δ3.25 (s, 3H, NCH3), δ3.2-2.7 (m, 1H, CH), and δ1.3-1.2 (d, 6H, C(CH3 (2).

Provenance & Evidence