2-Chloro-1,3-thiazole-5-sulfonamide → 2-[5-(4-Chloro-3-methyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiazole-5-sulfonic acid amide

HRID 670403Notes

Reaction equation

HRID 670403 reaction equation
[Cl:1][c:2]1[c:3]([CH3:23])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[CH:22])[cH:6][cH:7]1.[Cl:24][c:25]1[s:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][n:29]1>>[Cl:1][c:2]1[c:3]([CH3:23])[cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([c:12]([C:14]([F:15])([F:16])[F:17])[cH:13]2)[n:18][cH:19][c:20]3[C:21]#[C:22][c:25]2[s:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][n:29]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 220195182-Chloro-1,3-thiazole-5-sulfonamideHCID 866080535-(4-Chloro-3-methyl-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine

Product 1

HCID 670013582-[5-(4-Chloro-3-methyl-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidin-3-ylethynyl]-thiazole-5-sulfonic acid amide

Sources & evidence

ORD record
ord-01a558eaee184dbb95d577e06e540f08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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