Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) → Cholesta-5,7-diene-3,24,25-triol, (3beta,24R)-

Participants

Reaction Steps

Pyridinium p-toluenesulfonate (12.5 mg) was added to a solution of (24R)-5,7-cholestadiene-3β,24,25-triol 3-tetrahydropyranyl ether (25 mg) in 2 ml of ethanol in an argon stream under stirring, and the mixture was left to stand at room temperature for 2 days. The reaction mixture was evaporated with 40 ml of ethyl acetate. The organic layer was washed with saturated brine and dried over anhydrous sodium sulfate. The solvent was evaporated under reduced pressure to give 14 mg (67%) of (24R)-5,7-cholestadiene-3β,24,25-triol.

Provenance & Evidence