2,5-dichloro-N-(2-((1-methylethyl)sulfonyl)phenyl)-4-pyrimidinamine → 2-(2-{5-Chloro-4-[2-(propane-2-sulfonyl)-phenylamino]-pyrimidin-2-ylamino}-1-methoxy-6,7,8,9-tetrahydro-5H-benzocyclohepten-6-ylamino)-ethanol
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[CH:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1.[NH2:22][c:23]1[cH:24][cH:25][c:26]2[c:27]([c:37]1[O:38][CH3:39])[CH2:28][CH2:29][CH2:30][CH:31]([NH:33][CH2:34][CH2:35][OH:36])[CH2:32]2>>[c:2]1([NH:22][c:23]2[cH:24][cH:25][c:26]3[c:27]([c:37]2[O:38][CH3:39])[CH2:28][CH2:29][CH2:30][CH:31]([NH:33][CH2:34][CH2:35][OH:36])[CH2:32]3)[n:3][cH:4][c:5]([Cl:21])[c:6]([NH:8][c:9]2[c:10]([S:15](=[O:16])(=[O:17])[CH:18]([CH3:19])[CH3:20])[cH:11][cH:12][cH:13][cH:14]2)[n:7]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-cdb15196a41a43c29caf617b3299fcfd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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