Ethanol → 1-Boc-3-(aminomethyl)piperidine

HRID 670630Notes

Reaction equation

HRID 670630 reaction equation
[CH3:29][CH2:30][OH:31].[NH2:2][NH2:3].[O:4]=[C:5]1[N:6]([CH2:15][CH:16]2[CH2:17][N:18]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20][CH2:21]2)[C:13](=[O:14])[c:8]2[c:7]1[cH:12][cH:11][cH:10][cH:9]2.[OH2:1]>>[NH2:6][CH2:15][CH:16]1[CH2:17][N:18]([C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20][CH2:21]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 86649437tert-Butyl 3-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]piperidine-1-carboxylate

Product 1

HCID 27564831-Boc-3-(aminomethyl)piperidine

Sources & evidence

ORD record
ord-693652c162b241a0a7fad96820e91225
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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