3,5-Dichlorophenylboronic acid → N4-{2-[(2-aminopyrimidin-4-yl)amino]ethyl}-6-(3,5-dichlorophenyl)pyrimidine-2,4-diamine

HRID 670674Notes

Reaction equation

HRID 670674 reaction equation
[Cl:20][c:21]1[cH:22][c:23]([B:28]([OH:29])[OH:30])[cH:24][c:25]([Cl:27])[cH:26]1.[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][CH2:9][CH2:10][NH:11][c:12]2[n:13][c:14]([NH2:19])[n:15][c:16]([Cl:18])[cH:17]2)[n:7]1>>[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][CH2:9][CH2:10][NH:11][c:12]2[n:13][c:14]([NH2:19])[n:15][c:16](-[c:23]3[cH:22][c:21]([Cl:20])[cH:26][c:25]([Cl:27])[cH:24]3)[cH:17]2)[n:7]1

Participants

3

Reactant 2

HCID 27343313,5-Dichlorophenylboronic acidHCID 71681979N4-{2-[(2-aminopyrimidin-4-yl)amino]ethyl}-6-chloropyrimidine-2,4-diamine

Product 1

HCID 44609413N4-{2-[(2-aminopyrimidin-4-yl)amino]ethyl}-6-(3,5-dichlorophenyl)pyrimidine-2,4-diamine

Sources & evidence

ORD record
ord-8b34c10a6568453c9674561e00fc79d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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