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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 670738Generated: November 2, 2026

Tetrahydrofuran → 2-[(SR)-1-[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-2-(tert-butyldimethyl-silanyloxy)-ethoxy]-5-chloro-pyridine

https://huagongshe.com/reaction/670738

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
Reactant(RS)-1-[(3SR,4RS)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-2-(tert-butyl-dimethyl-silanyloxy)-ethanolHCID 67131474—
Reactant5-chloropyridin-2-olHCID 178516064—
Product2-[(SR)-1-[(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidin-3-yl]-2-(tert-butyldimethyl-silanyloxy)-ethoxy]-5-chloro-pyridineHCID 67131475—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-15804efc4c0d489dba95ac17d0181c35
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)