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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 670876Generated: October 30, 2026

Hydrochloric Acid → 5-[(2-chloro-4-fluorophenyl)acetyl]-1-(2,6-dichlorophenyl)pyridin-2(1H)-one

https://huagongshe.com/reaction/670876

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1,2-DibromoethaneHCID 7839—
Reactant1,2-DimethoxyethaneHCID 8071—
ReactantEthyl AcetateHCID 8857—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladiumHCID 23938—
ReactantZincHCID 23994—
Reactant1-(Bromomethyl)-2-chloro-4-fluorobenzeneHCID 2725062—
Reactant1-(2,6-Dichlorophenyl)-6-oxo-1,6-dihydropyridine-3-carbonylchlorideHCID 86616454—
Product5-[(2-chloro-4-fluorophenyl)acetyl]-1-(2,6-dichlorophenyl)pyridin-2(1H)-oneHCID 66670139—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-01c51373d7184e19a8a01d9a26e5bda9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)