Methanol → 3-(2-Chloro-4-methylamino-phenyl)-2-(2-chloro-pyridin-4-yl)-1,1,1-trifluoro-butan-2-ol
Reaction equation
[BH4-:27].[CH3:24][O-:25].[CH3:30][OH:31].[NH2:1][c:2]1[cH:3][c:4]([Cl:23])[c:5]([CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]2[cH:16][c:17]([Cl:21])[n:18][cH:19][cH:20]2)[CH3:22])[cH:6][cH:7]1.[Na+:26].[Na+:28].[OH2:29]>>[NH:1]([c:2]1[cH:3][c:4]([Cl:23])[c:5]([CH:8]([C:9]([C:10]([F:11])([F:12])[F:13])([OH:14])[c:15]2[cH:16][c:17]([Cl:21])[n:18][cH:19][cH:20]2)[CH3:22])[cH:6][cH:7]1)[CH3:24]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b77bdf2d46b1417a88eac198bb4b4cd7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…