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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 67099Generated: October 29, 2026

Thionyl Chloride → 6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

https://huagongshe.com/reaction/67099

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThionyl ChlorideHCID 24386—
Reactant6,7-Dihydroxychromon-3-carboxylic acidHCID 12200776—
Product6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chlorideHCID 12765757—

Reaction Steps

6,7-Dihydroxychromone-3-carboxylic acid (888 mg) and 25 ml of thionyl chloride were refluxed for one hour. Then, the thionyl chloride was removed by distillation, and after benzene was added, further distillation was conducted. Dichloromethane was added into the residue for solidification, whereby the desired product (719 mg) was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04344944
Source datasetuspto-grants-1982_08
ORD IDord-63fbe7f0b4634b799b24b98090e97e11
Source noteuspto-grants-1982_08