Dichloromethane → 4-(4-Trifluoromethoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester

HRID 671252Notes

Reaction equation

HRID 671252 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[Cl:29][CH2:30][Cl:31].[F:14][C:15]([O:16][c:17]1[cH:18][cH:19][c:20]([S:23](=[O:24])(=[O:25])[Cl:26])[cH:21][cH:22]1)([F:27])[F:28]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([S:23]([c:20]2[cH:19][cH:18][c:17]([O:16][C:15]([F:14])([F:27])[F:28])[cH:22][cH:21]2)(=[O:24])=[O:25])[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 143452tert-Butyl piperazine-1-carboxylateHCID 523102p-(Trifluoromethoxy)benzenesulphonyl chloride

Product 1

HCID 458629304-(4-Trifluoromethoxy-benzenesulfonyl)-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-95b8dcc6e3af4166ad99ed48babe3558
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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