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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 671498Generated: October 30, 2026

Tetrahydrofuran → Ethyl 1-((4-(5-(difluoro(phenyl)methyl)benzofuran-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylate

https://huagongshe.com/reaction/671498

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriisopropyl borateHCID 21531—
ReactantEthyl 1-(4-bromo-3-fluorobenzyl)azetidine-3-carboxylateHCID 58415312—
Reactant5-(Difluoro(phenyl)methyl)benzofuranHCID 58415360—
Reactant5-(Difluoro(phenyl)methyl)benzofuran-2-ylboronic acidHCID 67092147—
ReactantButyllithiumHCID 178418339—
ProductEthyl 1-((4-(5-(difluoro(phenyl)methyl)benzofuran-2-yl)-3-fluorophenyl)methyl)azetidine-3-carboxylateHCID 58415314—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-60791227ba6e41d08bb549646fbfe5c1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)