2,3,7-Tribromo-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester → 2,3-Dibromo-7-cyano-1-(2-methoxy-benzyl)-4-hydroxy-1H-pyrrolo[2,3-c]pyridine-5-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:27])[c:8]2[c:9]([c:10]([Br:12])[n:11]1)[n:13]([CH2:18][c:19]1[c:20]([O:25][CH3:26])[cH:21][cH:22][cH:23][cH:24]1)[c:14]([Br:17])[c:15]2[Br:16].[Cu:28][C:29]#[N:30]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7]([OH:27])[c:8]2[c:9]([c:10]([C:29]#[N:30])[n:11]1)[n:13]([CH2:18][c:19]1[c:20]([O:25][CH3:26])[cH:21][cH:22][cH:23][cH:24]1)[c:14]([Br:17])[c:15]2[Br:16]Participants
3
Sources & evidence
- ORD record
- ord-5fa0fc6116c9493085267dd77ae8412d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…