Methanethioic acid, O-ethyl ester → HCID 20528715, compound

HRID 67170Notes

Reaction equation

HRID 67170 reaction equation
[N:1]([CH2:4][CH2:5][CH2:6][CH:7]1[CH2:12][CH2:11][CH2:10][CH2:9][NH:8]1)=[N+:2]=[N-:3].[CH:13](OCC)=[S:14]>CCOCC>[CH:13]([N:8]1[CH2:9][CH2:10][CH2:11][CH2:12][CH:7]1[CH2:6][CH2:5][CH2:4][N:1]=[N+:2]=[N-:3])=[S:14]

Participants

4

Reactant 2

HCID 11073343Methanethioic acid, O-ethyl esterHCID 20528703HCID 20528703, compound

Product 1

HCID 20528715HCID 20528715, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

To a solution of 2-(3'-azidopropyl)-piperidine (1.8 g) in ether (10 ml) was added ethyl thioformate (1.5 ml). The solution was kept at 4° C. overnight and evaporated to leave an oil which was purified by chromatography on silica gel. The IR-spectrum (CHCl3) showed strong bands at 2950, 2100, 1485, 1445 and 1250 cm-1.

Workup

  1. customevaporated
  2. customto leave an oil which
  3. customwas purified by chromatography on silica gel

Sources & evidence

ORD record
ord-963a9e5dbab54ea3b4212a1ddb594c72
Source dataset
uspto-grants-1982_08
Patent number
US04345071

Reaction notes

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