HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodine → trans-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodine | HCID 807 | — |
| Reactant | cis-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide | HCID 58679826 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | trans-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide | HCID 10710192 | 26.3% |
Reaction Steps
A solution of cis-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide (1.9 g) and iodine (50 mg) in 500 mL toluene was irradiated for 5 days with a 100-watt incandescent light bulb. The solvent was removed in vacuo and the residue was recrystallized from toluene/methanol to give 0.50 g of trans-N-[4-(3-chlorophenyl)-but-3-enyl]-phthalimide (no cis-isomer was observed by 1H-NMR).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084154B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-4a13bbd2a60c451086842b48e8e24bdf |
| Source note | uspto-grants-2006_08 |