反应详情

2,5-undecadiyn-1-ol (1.5 g) in absolute ethanol (15 ml) was reduced with Lindlar catalyst (0.33 g) in the presence of quinoline (0.1 ml) at 25° C., 1 atm., for 7 h. The uptake of hydrogen stopped at 420 ml (theoretical 428 ml). The solution was filtered, and the solvent was evaporated to give 1.5 g of crude product which was then purified by column chromatography on silica gel (50 g). Elution with ether-petroleum ether (1:4 parts by volume) gave 1.07 g of (Z,Z)-2,5-undecadien-1-ol as an oil.

1. filtrationThe solution was filtered
2. customthe solvent was evaporated
3. customto give 1.5 g of crude product which
4. customwas then purified by column chromatography on silica gel (50 g)
5. washElution with ether-petroleum ether (1:4 parts by volume)