6-Chloro-2-piperazin-1-yl-quinoline → 9-{4-[4-(6-chloro-quinolin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Reaction equation
[Cl:27][c:28]1[cH:29][c:30]2[cH:31][cH:32][c:33]([N:38]3[CH2:39][CH2:40][NH:41][CH2:42][CH2:43]3)[n:34][c:35]2[cH:36][cH:37]1.[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][Br:24])[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]>>[F:1][C:2]([CH2:3][NH:4][C:5](=[O:6])[C:7]1([CH2:20][CH2:21][CH2:22][CH2:23][N:41]2[CH2:40][CH2:39][N:38]([c:33]3[cH:32][cH:31][c:30]4[cH:29][c:28]([Cl:27])[cH:37][cH:36][c:35]4[n:34]3)[CH2:43][CH2:42]2)[c:8]2[cH:9][cH:10][cH:11][cH:12][c:13]2-[c:14]2[cH:15][cH:16][cH:17][cH:18][c:19]21)([F:25])[F:26]Participants
3
Sources & evidence
- ORD record
- ord-081e22c8eec248b682cdab9522391725
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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