HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Hydroxy-2-naphthoic acid → 6-Hydroxy-2-naphthoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Hydroxy-2-naphthoic acid | HCID 7104 | — |
| Reactant | 2-Naphthol | HCID 8663 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Product | 6-Hydroxy-2-naphthoic acid | HCID 85557 | — |
Reaction Steps
In the carboxylation of the potassium salt of 2-hydroxynaphthalene, the initial product form is 3-hydroxy-2-naphthoic acid which subsequently rearranges in situ to form 6-hydroxy-2-naphthoic acid. It has been found that the conditions which favor the formation of 3-hydroxy-2-naphthoic acid in the Kolbe-Schmitt reaction hinder the rearrangement reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04345095 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-ea8f95bbc1594355b96abb88c08757be |
| Source note | uspto-grants-1982_08 |