1,4-Dioxane → N-[[3-(3-fluoro-4-pyridin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

HRID 672071Notes

Reaction equation

HRID 672071 reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][O:34][CH2:35]1.[CH3:20][Sn:21]([c:22]1[cH:23][cH:24][n:25][cH:26][cH:27]1)([CH3:28])[CH3:29].[F:1][c:2]1[cH:3][c:4]([N:9]2[C:10](=[O:19])[O:11][CH:12]([CH2:14][NH:15][C:16]([CH3:17])=[O:18])[CH2:13]2)[cH:5][cH:6][c:7]1[I:8]>>[F:1][c:2]1[cH:3][c:4]([N:9]2[C:10](=[O:19])[O:11][CH:12]([CH2:14][NH:15][C:16]([CH3:17])=[O:18])[CH2:13]2)[cH:5][cH:6][c:7]1-[c:22]1[cH:23][cH:24][n:25][cH:26][cH:27]1

Participants

4

Reactant 3

HCID 312751,4-DioxaneHCID 11128458Pyridine, 4-(trimethylstannyl)-HCID 11728568(S)-N-[3-(3-Fluoro-4-iodophenyl)-2-oxo-oxazolidin-5-ylmethyl]acetamide

Product 1

HCID 10381901N-[[3-(3-fluoro-4-pyridin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide

Sources & evidence

ORD record
ord-1ddaf3e59a4142779aa71b3b256b324b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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