4-Chloro-o-anisic acid → N-(1-azabicyclo[2.2.2]octan-3-yl)-4-chloro-2-methoxybenzamide

HRID 672209Notes

Reaction equation

HRID 672209 reaction equation
[Cl:23][c:24]1[cH:25][c:26]([O:33][CH3:34])[c:27]([C:28](=[O:29])[OH:30])[cH:31][cH:32]1.[N:1]12[CH2:2][CH:3]([NH:9][C:10](=[O:11])[c:12]3[cH:13][cH:14][c:15](-[c:16]4[s:17][cH:18][cH:19][cH:20]4)[cH:21][cH:22]3)[CH:4]([CH2:5][CH2:6]1)[CH2:7][CH2:8]2>>[N:1]12[CH2:2][CH:3]([NH:9][C:28]([c:27]3[c:26]([O:33][CH3:34])[cH:25][c:24]([Cl:23])[cH:32][cH:31]3)=[O:30])[CH:4]([CH2:5][CH2:6]1)[CH2:7][CH2:8]2

Participants

3

Reactant 2

HCID 936824-Chloro-o-anisic acidHCID 67326107N-(1-azabicyclo[2.2.2]octan-3-yl)-4-thiophen-2-ylbenzamide

Product 1

HCID 67326242N-(1-azabicyclo[2.2.2]octan-3-yl)-4-chloro-2-methoxybenzamide

Sources & evidence

ORD record
ord-8dcddb08b5744d55bdd268d6cd001e23
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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