Acetone → Ethyl 2-[4-(cyanomethoxy)phenyl]-2-ethoxycarbonylacetate

HRID 672300Notes

Reaction equation

HRID 672300 reaction equation
[Br:19][CH2:20][C:21]#[N:22].[C:23](=[O:24])([O-:25])[O-:26].[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[c:12]1[cH:13][cH:14][c:15]([OH:18])[cH:16][cH:17]1.[CH3:29][C:30](=[O:31])[CH3:32].[K+:27].[K+:28]>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[CH:6]([C:7](=[O:8])[O:9][CH2:10][CH3:11])[c:12]1[cH:13][cH:14][c:15]([O:18][CH2:20][C:21]#[N:22])[cH:16][cH:17]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 11534BromoacetonitrileHCID 19660Carbonate IonHCID 12965552HCID 12965552, compound

Product 1

HCID 21844455Ethyl 2-[4-(cyanomethoxy)phenyl]-2-ethoxycarbonylacetate

Sources & evidence

ORD record
ord-5b188bf206aa42f5bae774526f9c5d2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…