HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Phenyl-but-3-ynyl)-carbamic acid tert-butyl ester → 4-Phenyl-but-3-ynylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Phenyl-but-3-ynyl)-carbamic acid tert-butyl ester | HCID 23544319 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | 4-Phenyl-but-3-ynylamine | HCID 15642991 | — |
Reaction Steps
A solution of (4-phenyl-but-3-ynyl)-carbamic acid tert-butyl ester (98 mg) was stirred for 0.5 h in 1:1 trifluoroacetic acid/dichloromethane (10 ml). The volatile materials were evaporated to give the crude 4-phenyl-but-3-ynylamine, which was used in subsequent transformations without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084154B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-20d2e46c1d1247a2976c93d528f9a3be |
| Source note | uspto-grants-2006_08 |