Dimethyl Sulfoxide → Tert-butyl 3-[tert-butyl(dimethyl)silyl]oxy-2-[1-(3-chloro-4-cyano-2-methylanilino)ethyl]pyrrolidine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]([CH3:22])[NH2:23])[CH:10]([O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12]1.[C:46](=[O:47])([O-:48])[O-:49].[CH3:108][c:109]1[cH:110][cH:111][cH:112][cH:113][cH:114]1.[CH3:24][c:25]1[cH:26][cH:27][cH:28][cH:29][cH:30]1.[CH3:31][S:32]([CH3:33])=[O:34].[Cl:35][c:36]1[c:37]([C:38]#[N:39])[cH:40][cH:41][c:42]([I:45])[c:43]1[CH3:44].[Cs+:50].[Cs+:51].[O:54]=[C:55]([CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1.[O:72]=[C:73]([CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1)[CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1.[O:90]=[C:91]([CH:92]=[CH:93][c:94]1[cH:95][cH:96][cH:97][cH:98][cH:99]1)[CH:100]=[CH:101][c:102]1[cH:103][cH:104][cH:105][cH:106][cH:107]1.[Pd:52].[Pd:53]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:21]([CH3:22])[NH:23][c:42]2[cH:41][cH:40][c:37]([C:38]#[N:39])[c:36]([Cl:35])[c:43]2[CH3:44])[CH:10]([O:13][Si:14]([CH3:15])([CH3:16])[C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-f72b4b33589144efa1d63c971998acf2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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