6-chloro-N-[2-(4-methylpiperazin-1-ylmethyl)phenyl]nicotinamide → N-[2-(4-Methylpiperazin-1-ylmethyl)phenyl]-6-[5-(thiophen-3-ylcarbonylamino)-2-methyl-phenyl]-nicotinamide
Reaction equation
[CH3:25][c:26]1[c:27]([B:40]2[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]2)[cH:28][c:29]([NH:32][C:33](=[O:34])[c:35]2[cH:36][s:37][cH:38][cH:39]2)[cH:30][cH:31]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[c:10]([CH2:15][N:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[cH:11][cH:12][cH:13][cH:14]2)[cH:23][cH:24]1>>[c:2]1(-[c:27]2[c:26]([CH3:25])[cH:31][cH:30][c:29]([NH:32][C:33](=[O:34])[c:35]3[cH:36][s:37][cH:38][cH:39]3)[cH:28]2)[n:3][cH:4][c:5]([C:6](=[O:7])[NH:8][c:9]2[c:10]([CH2:15][N:16]3[CH2:17][CH2:18][N:19]([CH3:22])[CH2:20][CH2:21]3)[cH:11][cH:12][cH:13][cH:14]2)[cH:23][cH:24]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-b8b4a7b96e2d4750af2b0aa8f9d92d83
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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