N-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamide → 3-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(3-methanesulfonylamino-2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamide

HRID 672986Notes

Reaction equation

HRID 672986 reaction equation
[CH3:19][O:20][C:21]([c:22]1[cH:23][c:24](-[n:29]2[cH:30][n:31][c:32](-[c:34]3[cH:35][n:36][n:37](-[c:41]4[cH:42][cH:43][cH:44][cH:45][cH:46]4)[c:38]3[CH2:39][CH3:40])[cH:33]2)[c:25]([CH3:28])[cH:26][cH:27]1)=[O:47].[NH2:1][c:2]1[c:3]([O:17][CH3:18])[c:4]([NH:12][S:13](=[O:14])(=[O:15])[CH3:16])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[NH:1]([c:2]1[c:3]([O:17][CH3:18])[c:4]([NH:12][S:13](=[O:14])(=[O:15])[CH3:16])[cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1)[C:21](=[O:20])[c:22]1[cH:23][c:24](-[n:29]2[cH:30][n:31][c:32](-[c:34]3[cH:35][n:36][n:37](-[c:41]4[cH:42][cH:43][cH:44][cH:45][cH:46]4)[c:38]3[CH2:39][CH3:40])[cH:33]2)[c:25]([CH3:28])[cH:26][cH:27]1

Participants

3

Reactant 2

HCID 22506980N-(3-amino-2-methoxy-5-trifluoromethyl-phenyl)-methanesulfonamideHCID 588614453-[4-(5-ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-4-methyl-benzoic acid methyl ester

Product 1

HCID 210970943-[4-(5-Ethyl-1-phenyl-1H-pyrazol-4-yl)-imidazol-1-yl]-N-(3-methanesulfonylamino-2-methoxy-5-trifluoromethyl-phenyl)-4-methyl-benzamide

Sources & evidence

ORD record
ord-6690d4c4df7b4c85a31900a88a11c73a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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