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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 673125Generated: October 25, 2026

Chlorotrimethylsilane → Tert-butyl 4-(5-chloropyridin-2-yl)piperidine-1-carboxylate

https://huagongshe.com/reaction/673125

Reaction equation

Participants

RoleNameHCIDCharge
ReactantChlorotrimethylsilaneHCID 6397—
Reactant1,2-DibromoethaneHCID 7839—
ReactantTetrahydrofuranHCID 8028—
ReactantPalladiumHCID 23938—
ReactantDibenzylidene acetoneHCID 95417—
Reactant2-Bromo-5-chloropyridineHCID 817098—
ReactantTert-butyl 4-iodopiperidine-1-carboxylateHCID 10892302—
ProductTert-butyl 4-(5-chloropyridin-2-yl)piperidine-1-carboxylateHCID 66850771—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-ff1d7448375b4a36b76cfe55d96020f7
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)