2-Amino-3-cyclopropylpropanamide → N-(1-amino-3-cyclopropyl-1-oxopropan-2-yl)-6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide

HRID 673307Notes

Reaction equation

HRID 673307 reaction equation
[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:21][CH:22]([C:23](=[O:24])[NH2:25])[CH2:26][CH:27]1[CH2:28][CH2:29]1>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:21][CH:22]([C:23](=[O:24])[NH2:25])[CH2:26][CH:27]3[CH2:28][CH2:29]3)[n:11]2)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 197367572-Amino-3-cyclopropylpropanamideHCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

Product 1

HCID 78010107N-(1-amino-3-cyclopropyl-1-oxopropan-2-yl)-6-(cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)pyridine-2-carboxamide

Sources & evidence

ORD record
ord-00344fcf595b477ebf8829276dba43d9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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